SSR 180711 hydrochloride

SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus[1].


Cat. No.: EX-A15434	Purity: >98%

	Chemical structure of SSR 180711 hydrochloride

For research only, Do not use for Human!

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CAS No.	446031-79-4
Purity	>98%
Formula	C14H18BrClN2O2
Mol Weight	361.662
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bruno Biton, et al. SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (1) binding and functional profile. Neuropsychopharmacology. 2007 Jan;32(1):1-16.
CoA	CoA of SSR 180711 hydrochloride

Smiles:	C1CN2CCC1N(CC2)C(=O)OC3=CC=C(C=C3)Br.Cl


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