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Product Information:

SSP-DM4

sulfo-SPDB-DM4 is a agent-linker conjugate for ADC by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker.

Cat. No.: EX-A5869    Purity: >95%
Chemical
Chemical structure of SSP-DM4


For research only, Do not use for Human!

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Synonymssulfo-SPDB-DM4
CAS No.1626359-59-8
Purity>95%
FormulaC46H63ClN4O17S3
Mol Weight1075.657
ColorWhite to yellow
Statesolid powder
SolubilitySoluble in DMSO 50 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -80°C, protect from light, stored under nitrogen;
ShippingDry ice shipping upon request
 
 
Reference:  

[1]. Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.

CoACoA of SSP-DM4

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