SSK1

SSK1, a senescence-specific killing compound, is a β-galactosidase-targeted proagent attenuates inflammation. SSK1 is activated by lysosomal β-galactosidase and selectively killed senescent cells through the activation of p38 MAPK and induction of apoptosis .


Cat. No.: EX-A15496	Purity: >98%

	Chemical structure of SSK1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	441	in_stock
25mg	892	in_stock
50mg	1376	in_stock
100mg	2268	in_stock
250mg	4542	in_stock
500mg	7300	in_stock

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CAS No.	2629250-69-5
Purity	>98%
Formula	C31H34F2N4O18
Mol Weight	788.6145
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture and light; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Yusheng Cai, et al. Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice. Cell Res. 2020 Jul;30(7):574-589.
CoA	CoA of SSK1

Smiles:	CC(O[C@H]([C@H]([C@H]1OC(C)=O)OC(C)=O)[C@@H](O[C@@H]1COC(C)=O)OC(C=CC(COC(NC(C=CN2[C@](C(F)([C@@H]3O)F)([H])O[C@@H]3CO)=NC2=O)=O)=C4)=C4[N+]([O-])=O)=O


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