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Product Information:

SQ109

SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent.

Cat. No.: EX-A764    Purity: >98%
Chemical
Chemical structure of SQ109


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg807in_stock
250mg1557in_stock
500mg2488in_stock
1g3973in_stock
2g6290in_stock
5g15915in_stock


CAS No.502487-67-4
Purity>98%
FormulaC22H38N2
Mol Weight330.5505
ColorLight yellow to yellow
StateSolid-Liquid Mixture
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Veiga-Santos P, et al. SQ109, a new drug lead for Chagas disease. Antimicrob Agents Chemother. 2015 Apr;59(4):1950-61.

[2].Jia L, et al. Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug. Br J Pharmacol. 2005 Jan;144(1):80-7

[3].Jia L, et al. Interspecies pharmacokinetics and in vitro metabolism of SQ109. Br J Pharmacol. 2006 Mar;147(5):476-85.

CoACoA of SQ109
Smiles:C\C(C)=C/CC\C(C)=C\CNCCNC1C2CC3CC(C2)CC1C3

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