SP-471

SP-471 is a potent dengue virus (DENV) protease inhibitor with IC50 value of 18 μM. SP-471 inhibits both intermolecular and intramolecular protease processes of DENV.


Cat. No.: EX-A17050	Purity: >98%

	Chemical structure of SP-471

For research only, Do not use for Human!

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Synonyms	3-[9-[(3-bromophenyl)methyl]-6-(3-carbamimidoylphenyl)carbazol-3-yl]benzenecarboximidamide
CAS No.	2768010-39-3
Purity	>98%
Formula	C33H26BrN5
Mol Weight	572.497
Color	White to off-white
State	Solid
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, stored under nitrogen; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Swarbrick C, Zogali V, Chan KWK, et al. Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease. Eur J Med Chem. 2021;224:113695.
CoA	CoA of SP-471

Smiles:	N=C(C1=CC=CC(C2=CC=C3C(C4=C(N3CC5=CC=CC(Br)=C5)C=CC(C6=CC=CC(C(N)=N)=C6)=C4)=C2)=C1)N


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