Sovleplenib

Sovleplenib (HMPL-523) is a highly potent, orally available and selective SYK inhibitor with an IC50 of 25 nM. Anti-tumor activity. Sovleplenib can be used for the research of immune thrombocytopenia (ITP).


Cat. No.: EX-A7664	Purity: >98%

	Chemical structure of Sovleplenib

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	665	In-stock
1g	965	In-stock
5g	3565	In-stock

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Synonyms	HMPL-523
CAS No.	1415792-84-5
Purity	>98%
Formula	C24H30N6O3S
Mol Weight	482.598
Color	Light yellow to yellow
State	solid powder
Solubility	DMSO : 25 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Su WG, et al. Preparation of pyridopyrazine derivatives for use as Syk inhibitors. WO2012167733 A1. [2]. Na Yang, et al. HMPL-523, a Novel SYK Inhibitor Showed Anti-Tumor Activities In Vitro and In Vivo. Blood (2016) 128 (22): 3970.
CoA	CoA of Sovleplenib


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