Soficitinib

Soficitinib (Compound 20) is a selective tyrosine kinase 2 (TYK2) and Janus kinase 2 (JAK2) inhibitor, with IC50 values of 0.5 nM and 1.2 nM, respectively. Soficitinib shows promise for research into autoimmune diseases (such as psoriasis, rheumatoid arthritis) and inflammatory diseases .


Cat. No.: EX-A16432	Purity: >98%

	Chemical structure of Soficitinib

For research only, Do not use for Human!

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25mg	get quote

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Synonyms	ICP-332
Synonyms 2	ICP332
CAS No.	2574524-67-5
Purity	>98%
Formula	C18H21ClN8O
Mol Weight	400.865
Color	White to off-white
State	solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Heterocyclic compound, preparation method and application thereof in medicine and pharmacology. CN112142743A. 2020-12-29.
CoA	CoA of Soficitinib

Smiles:	C[C@]12[C@](CN(C1)C3=NC(NC=4C=NN(C)C4)=NC=C3Cl)(CN(C(CC#N)=O)C2)[H]


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