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Product Information:

SMN2 splicing modulator TEC-1

SMN2 splicing modulator TEC-1 is a novel specific, CNS penetrant small molecule SMN2 splicing modulator, increases the expression level of FL-SMN2 mRNA and decreases the expression level of Δ7 mRNA.

Cat. No.: EX-A6552    Purity: >98%
Chemical
Chemical structure of SMN2 splicing modulator TEC-1


For research only, Do not use for Human!

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CAS No.2407723-70-8
Purity>98%
FormulaC21H23N7O
Mol Weight389.4536
Statesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ando, Shiori et al. “Discovery of a CNS penetrant small molecule SMN2 splicing modulator with improved tolerability for spinal muscular atrophy.” Scientific reports vol. 10,1 17472. 15 Oct. 2020

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