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Product Information:

SMIP34

PELP1-IN-1 is a PELP1 inhibitor. SMIP34 reduces cell viability and colony formation. PELP1-IN-1 induces apoptosis and cell cycle arrest at S phase. PELP1-IN-1 decreases the expression of PELP1. PELP1-IN-1 shows antitumor activity. SMIP34 has the potential for the research of triple-negative breast cancer (TNBC) .

Cat. No.: EX-A10371    Purity: >98%
Chemical
Chemical structure of SMIP34


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
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100mg885Inquire
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CAS No.946262-80-2
Purity>98%
FormulaC20H15ClFN5O2S
Mol Weight443.882
Colorwhite to off-white
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Altwegg KA, et al. Targeting PELP1 oncogenic signaling in TNBC with the small molecule inhibitor SMIP34. Breast Cancer Res Treat. 2023 Jul;200(1):151-162.

CoACoA of SMIP34
Smiles:O=C1C2=C(N(C3=CC=C(Cl)C=C3)N=C2)N=C(SCC(NCC4=CC=C(F)C=C4)=O)N1

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