SMER3

SMER3, a Rapamycin enhancer, is a selective Skp1-Cullin-F-box (SCF)Met30 ubiquitin ligase inhibitor. SMER3 enhances Rapamycin's growth inhibitory effect by inhibition of SCFMet30[1].


Cat. No.: EX-A14862	Purity: >98%

	Chemical structure of SMER3

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1g	650	In-stock
2g	1060	In-stock
5g	2540	In-stock

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CAS No.	67200-34-4
Purity	>98%
Formula	C11H4N4O2
Mol Weight	224.1751
Color	Light yellow to green yellow
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mariam Aghajan, et al. Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nat Biotechnol. 2010 Jul;28(7):738-42.
CoA	CoA of SMER3

Smiles:	C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O


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