SMCC-DM1

SMCC-DM1 (DM1-SMCC) is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody drug conjugate (ADC).


Cat. No.: EX-A2653	Purity: >98%

	Chemical structure of SMCC-DM1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	985	In-stock
250mg	1385	In-stock
500mg	1900	In-stock
1g	3000	In-stock
2g	5600	In-stock

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Synonyms	DM1-SMCC
CAS No.	1228105-51-8
Purity	>98%
Formula	C51H66ClN5O16S
Mol Weight	1072.612
Color	white
State	solid
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Shao S, et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg Med Chem Lett. 2018 May 1;28(8):1363-1370.
CoA	CoA of SMCC-DM1

Smiles:	[H][C@@]12C[C@@](O)(NC(=O)O1)[C@H](OC)\C=C\C=C(C)\CC1=CC(OC)=C(Cl)C(=C1)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCSC1CC(=O)N(CC3CCC(CC3)C(=O)ON3C(=O)CCC3=O)C1=O)[C@]1(C)O[C@H]1[C@@H]2C


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