background


Product Information:

SKF-82958 hydrobromide

SKF-82958 ((±)-SKF 82958) hydrobromide is a dopamine D1 receptor full agonist (K0.5=4 nM), displays selective for D1 over D2 receptors (K0.5=73 nM). SKF-82958 hydrobromide induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC50=491 nM)[1].

Cat. No.: EX-A15210    Purity: >98%
Chemical
Chemical structure of SKF-82958 hydrobromide


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg750Inquire
250mg1250Inquire
1g2450Inquire
5gget quoteInquire


Synonyms(±)-SKF-82958 hydrobromide; Chloro-APB hydrobromide
CAS No.74115-01-8
Purity>98%
FormulaC19H21BrClNO2
Mol Weight410.733
ColorWhite to off-white
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Mottola DM, et al. Conformational analysis of D1 dopamine receptor agonists: pharmacophore assessment and receptor mapping. J Med Chem. 1996;39(1):285-296.

[2]. Haile CN, et al. The dopamine D(1) receptor agonist SKF-82958 serves as a discriminative stimulus in the rat. Eur J Pharmacol. 2000;388(2):125-131.

[3]. Mayorga AJ, et al. Striatal and nigral D1 mechanisms involved in the antiparkinsonian effects of SKF 82958 (APB): studies of tremulous jaw movements in rats. Psychopharmacology (Berl). 1999;143(1):72-81.

CoACoA of SKF-82958 hydrobromide
Smiles:C=CCN1CCC2=C(C(=C(C=C2C(C1)C3=CC=CC=C3)O)O)Cl.Br

KEYWORDS: buy SKF-82958 hydrobromide | SKF-82958 hydrobromide supplier | purchase | cost | manufacturer | order | distributor | buy 74115-01-8 | 74115-01-8 supplier