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Product Information:

SJF1528

SJF 1528 is a potent EGFR Degrader. It also degrades HER2.

Cat. No.: EX-A5078    Purity: >98%
Chemical
Chemical structure of SJF1528


For research only, Do not use for Human!

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SynonymsSJF 1528
Synonyms 2SJF-1528
CAS No.2230821-38-0
Purity>98%
FormulaC55H57ClFN7O8S
Mol Weight1030.6
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 103.06 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Burslem et al (2018) The advantages of targeted protein degradation over inhibition: An RTK case study. Cell Chem.Biol. 25 67 PMID: 29129716
CoACoA of SJF1528
Smiles:CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(COCCOCCOC4=CC=C(C5=CC6=C(N=CN=C6NC7=CC(Cl)=C(C=C7)OCC8=CC(F)=CC=C8)C=C5)C=C4)=O)=O)O)=O)SC=N1

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