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Product Information:

SIRT6 activator 12q

SIRT6 activator 12q is potent, selective and orally active SIRT6 activator with IC50 values of 171.20, >200, >200, >200, 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q induces Apoptosis and cell cycle arrest at G2 phase. SIRT6 activator 12q shows anticancer activity.

Cat. No.: EX-A5822    Purity: >98%
Chemical
Chemical structure of SIRT6 activator 12q


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg650In-stock
100mg950In-stock
200mg1550In-stock
1g3300In-stock


CAS No.2601734-99-8
Purity>98%
FormulaC31H22N2O2
Mol Weight454.5186
Color Off-white to yellow
Statesolid powder
SolubilitySoluble in DMSO 25 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Chen X, et al. Discovery of Potent Small-Molecule SIRT6 Activators: Structure-Activity Relationship and Anti-Pancreatic Ductal Adenocarcinoma Activity. J Med Chem. 2020 Sep 24;63(18):10474-10495.

CoACoA of SIRT6 activator 12q

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