SIRT-IN-4

SIRT-IN-4 is an inhibitor of the NAD+-dependent lysine deacetylase Sirtuin2 (Sirt2) (IC50=0.35 μM). SIRT-IN-4 is a potent Sirt2 deacetylase inhibitor that reduces cell survival and inhibits the migration of prostate cancer cells. SIRT-IN-4 can be used to study Sirt2 in cell cycle regulation, gene expression regulation, etc .


Cat. No.: EX-A17394	Purity: >98%

	Chemical structure of SIRT-IN-4

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	650	Inquire
10mg	750	Inquire
25mg	1150	Inquire

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CAS No.	3052115-51-9
Purity	>98%
Formula	C29H28ClFN4O2
Mol Weight	519.01

Reference:	[1].Colcerasa A, et al. Structure–Activity Studies of 1, 2, 4-Oxadiazoles for the Inhibition of the NAD+-Dependent Lysine Deacylase Sirtuin 2[J]. Journal of Medicinal Chemistry, 2023.
CoA	CoA of SIRT-IN-4

Smiles:	FC1=CC=CC(CN2CCCC(C2)CC3=NC(C4=CC=C(C=C4)NC(C5=CC=C(C=C5)Cl)=O)=NO3)=C1C


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