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Product Information:

SIRT-IN-2

SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 μM, respectively.

Cat. No.: EX-A5171    Purity: >98%
Chemical
Chemical structure of SIRT-IN-2


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg685In-stock
50mg985In-stock
100mg1485In-stock
200mg2200In-stock


CAS No.1431411-66-3
Purity>98%
FormulaC15H21N5O3S2
Mol Weight383.489
ColorYellow to brown
Statesolid powder
SolubilitySoluble in DMSO 62.5 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Disch JS, et al. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3. J Med Chem. 2013 May 9;56(9):3666-79.
CoACoA of SIRT-IN-2
Smiles:NC(C1=CC2=NC=NC(N3CCC(CCNS(C)(=O)=O)CC3)=C2S1)=O

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