Simpinicline

Simpinicline (OC-02), a highly selective nicotinic acetylcholine receptor (nAChR) agonist, shows potent antiviral activity against the SARS-CoV-2 variants in cell culture with an IC50 of 0.04 µM .


Cat. No.: EX-A15605	Purity: >98%

	Chemical structure of Simpinicline

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
250mg	2982	Inquire
500mg	4476	Inquire

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Synonyms	OC-02
CAS No.	753015-44-0
Purity	>98%
Formula	C10H13N3
Mol Weight	175.2303
Color	Yellow to brown
State	Oil
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Quik M, et al. α4β2 Nicotinic receptors play a role in the nAChR-mediated decline in L-dopa-induced dyskinesias in parkinsonian rats. Neuropharmacology. 2013 Aug;71:191-203.
CoA	CoA of Simpinicline

Smiles:	C(=C/[C@H]1CCNC1)\C=2C=NC=NC2


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