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Product Information:

SGD-1882

SGD-1882 (PBD dimer, Pyrrolobenzodiazepine dimer) is a novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).

Cat. No.: EX-A6227    Purity: >98%
Chemical
Chemical structure of SGD-1882


For research only, Do not use for Human!

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SynonymsPBD dimer
Synonyms 2Pyrrolobenzodiazepine dimer
CAS No.1222490-34-7
Purity>98%
FormulaC42H39N5O7
Mol Weight725.7884
Color Light yellow to yellow
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Eunhee G. Kim, et al. Strategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer Therapeutics. Biomol Ther (Seoul). 2015 Nov; 23(6): 493-509.

[2]. Dowdy Jackson, et al. Using the Lessons Learned From the Clinic to Improve the Preclinical Development of Antibody Drug Conjugates. Pharm Res. 2015; 32(11): 3458-3469.

CoACoA of SGD-1882

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