SGC-CK2-1

SGC-CK2-1 is a potent and highly selective casein 2 (CK2, CKII) inhibitor (CK2α/CK2α' IC50 = 4.2/2.3 nM by cell-free enzyme assay; DYRK2 IC50 = 440 nM, IC50≥3.4 μM against 465 other kinases).


Cat. No.: EX-A5080	Purity: >98%

	Chemical structure of SGC-CK2-1

For research only, Do not use for Human!

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CAS No.	2470424-39-4
Purity	>98%
Formula	C20H21N7O
Mol Weight	375.427
Color	Off-white to light yellow
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Carrow I Wells, et al. Development of a potent and selective chemical probe for the pleiotropic kinase CK2. Cell Chem Biol. 2021 Apr 15;28(4):546-558.e10. [2]. Marco P Licciardello, et al. A New Chemical Probe Challenges the Broad Cancer Essentiality of CK2. Trends Pharmacol Sci. 2021 May;42(5):313-315.
CoA	CoA of SGC-CK2-1


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