Segigratinib hydrochloride

Segigratinib hydrochloride (3D185) is a potent inhibitor of FGFR1/2/3 and CSF-1R; The IC50 values for FGFR1, FGFR2, FGFR3 and CSF-1R are 0.5, 1.3, 3.6 and 3.8 nM, respectively. Segigratinib hydrochloride has antitumor activity.


Cat. No.: EX-A13175	Purity: >98%

	Chemical structure of Segigratinib hydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
1g	get quote

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	2847066-15-1
Purity	>98%
Formula	C27H29Cl3N6O3
Mol Weight	591.917
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Peng X, et al. Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models. J Exp Clin Cancer Res. 2019 Aug 22;38(1):372.
CoA	CoA of Segigratinib hydrochloride

Smiles:	O=C(C1=CC=C(N2CCNC(C)(C2)C)C=C1)NC3=NNC4=C3C=CC(C5=C(Cl)C(OC)=CC(OC)=C5Cl)=N4.Cl


		Search