Seco-DUBA

Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups, which can each be used for coupling to an antibody via a linker. Seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs).


Cat. No.: EX-A6014	Purity: >95%

	Chemical structure of Seco-DUBA

For research only, Do not use for Human!

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CAS No.	1227961-59-2
Purity	>95%
Formula	C29H23ClN4O4
Mol Weight	526.97
Color	Light yellow to brown
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	-20℃, stored under nitrogen In solvent : -80℃, 6 months; -20℃, 1 month (stored under nitrogen)
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Elgersma RC, et al. Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody-Drug Conjugate SYD985. Mol Pharm. 2015;12(6):1813-1835.
CoA	CoA of Seco-DUBA


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