SPI-112Me

SPI-112Me is a prodrug for SPI-112, which preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by a factor of 20 in cell-free assays.


Cat. No.: EX-A3387	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
250mg	Get quote	In-stock
1g	Get quote	In-stock

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CAS No.	1243685-62-2
Purity	>98%
Formula	C23H19FN4O5S
Mol Weight	482.484
Appearance	Solid powder
Solubility	Soluble in DMSO, not in water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Win-Piazza, H., Schneeberger, V., Chen, L., Pernazza, D., Lawrence, H., & Sebti, S. et al. (2012). Enhanced anti-melanoma efficacy of interferon alfa-2b via inhibition of Shp2. Cancer Lett. 320(1):81-5. doi: 10.1016/j.canlet.2012.01.034
CoA	CoA of SPI-112Me

Smiles:	O=C(OC)C1=CC=CC(/N=N/C2=C(O)NC3=C2C=C(S(=O)(NCC4=CC=C(F)C=C4)=O)C=C3)=C1


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