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Product Information:

ZAP-180013

ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 μM. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs).

Cat. No.: EX-A4663    Purity: >98%
ZAP-180013
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mgGet quoteIn-stock
250mg750In-stock
500mg1100In-stock
1g1600In-stock
5g48852-4 weeks


CAS No.873080-25-2
Purity>98%
FormulaC19H17Cl2N3O4S
Mol Weight454.327
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Patrick R Visperas, et al. Identification of Inhibitors of the Association of ZAP-70 With the T Cell Receptor by High-Throughput Screen. SLAS Discov. 2017 Mar;22(3):324-331.
CoACoA of ZAP-180013
Smiles:O=C(C1=NC(S(=O)(CC)=O)=NC=C1Cl)N(CC2=CC=C(Cl)C=C2)CC3=CC=CO3

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