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Product Information:

K-Ras-PDEδ-IN-1

K-Ras-PDEδ-IN-1 is a novel and potent competitive K-Ras-PDEδ inhibitor. K-Ras-PDEδ-IN-1 binds to the farnesyl binding pocket of PDEδ with a low nanomolar Kd of 8 nM.

Cat. No.: EX-A4631    Purity: >98%
K-Ras-PDEδ-IN-1
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg700In-stock
100mg950In-stock
250mg1550In-stock
5g70006 weeks


CAS No.1841464-21-8
Purity>98%
FormulaC25H26FN5O2
Mol Weight447.5046
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Sandip Murarka, et al. Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding Site. Chemistry. 2017 May 2;23(25):6083-6093.
CoACoA of K-Ras-PDEδ-IN-1
Smiles:O=C(NCCC1=CC=C(F)C=C1)CCCN2N=C(C)C3=CN(C4=CC=C(C)C=C4)N=C3C2=O

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