CGP60474

CGP60474, a highly potent anti-endotoxemic agent, is a potent cyclin-dependent kinase (CDK) inhibitor. CGP60474 is a selective and ATP-competitive PKC inhibitor.


Cat. No.: EX-A4558	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	465	In-stock
250mg	725	In-stock
500mg	985	In-stock
1g	1485	In-stock
2g	2285	In-stock
5g	4600	In-stock

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CAS No.	164658-13-3
Purity	>98%
Formula	C18H18ClN5O
Mol Weight	355.821
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Jorda R, et al. How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?. J Med Chem. 2018;61(20):9105-9120. [2]. Han HW, et al. LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent. Sci Rep. 2018;8(1):14969. Published 2018 Oct 8. [3]. Stanetty P, et al. Novel and efficient access to phenylamino-pyrimidine type protein kinase C inhibitors utilizing a Negishi cross-coupling strategy. J Org Chem. 2005;70(13):5215-5220.
CoA	CoA of CGP60474

Smiles:	ClC1=CC(NC2=NC=CC(C3=CC=NC(NCCCO)=C3)=N2)=CC=C1


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