Olutasidenib

Olutasidenib (FT-2102) is a highly potent, orally active, brain penetrant and selective inhibitor of mutant Isocitrate dehydrogenase 1 (IDH1), with IC50 values of 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively.


Cat. No.: EX-A4523	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	600	In-stock
100mg	800	In-stock
250mg	1250	In-stock
500mg	1700	In-stock
1g	2385	In-stock
5g	5885	In-stock

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Synonyms	FT-2102
CAS No.	1887014-12-1
Purity	>98%
Formula	C18H15ClN4O2
Mol Weight	354.79
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. JM Watts, et al. A phase 1 dose escalation study of the IDH1m inhibitor, FT-2102, in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). [2]. Justin A. Caravella, et al. Structure-based design and identification of FT-2102 (olutasidenib), a potent mutant-selective IDH1 inhibitor. J Med Chem. 2020.
CoA	CoA of Olutasidenib

Smiles:	N#CC1=CC=C(N[C@H](C2=CC3=C(NC2=O)C=CC(Cl)=C3)C)C(N1C)=O


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