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Product Information:

dBRD9

dBRD9 is a PROTAC, can selective degrades BRD9. dBRD9 improves the bromine domain binding profile and reduces the binding activity of the whole BET family.

Cat. No.: EX-A4449    Purity: >98%
dBRD9
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg700In-stock
50mg1000In-stock
100mg1400In-stock
200mg1950In-stock
500mg2750In-stock
1g3950In-stock


CAS No.2170679-45-3
Purity>98%
FormulaC40H45N7O10
Mol Weight783.8262
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Remillard D, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Angew Chem Int Ed Engl. 2017 May 15;56(21):5738-5743.

CoACoA of dBRD9
Smiles:CN1C=C(C2=C(C1=O)C=NC=C2)C3=CC(=C(C(=C3)OC)CN(C)CC(=O)NCCOCCOCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)OC

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