JH-VIII-157-02

JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.


Cat. No.: EX-A4420	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	785	In-stock
50mg	1050	In-stock
100mg	1550	In-stock
250mg	2150	In-stock
500mg	2850	In-stock
1g	Get quote	inquire

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CAS No.	1639422-97-1
Purity	>98%
Formula	C28H27N5O2
Mol Weight	465.5463
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hatcher JM, et al. Discovery of Inhibitors That Overcome the G1202R Anaplastic Lymphoma Kinase Resistance Mutation. J Med Chem. 2015 Dec 10;58(23):9296-9308.
CoA	CoA of JH-VIII-157-02

Smiles:	O=C(N(C)C)CN1N=CC(C2=C(CC)C=C3C(C(C)(C)C(NC4=C5C=CC(C#N)=C4)=C5C3=O)=C2)=C1


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