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Product Information:

Tecovirimat

Tecovirimat (ST-246) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat is developed for the treatment of smallpox infection.

Cat. No.: EX-A4340    Purity: >98%
Tecovirimat
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg450In-stock
50mg585In-stock
100mg885In-stock
250mg1285In-stock
500mg1985In-stock
5g6500In-stock


SynonymsST-246
Synonyms 2Arestvyr
CAS No.869572-92-9
Purity>98%
FormulaC19H15F3N2O3
Mol Weight376.3292
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yang, Guang et al. An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus Challenge. Journal of virology vol. 79,20 (2005): 13139-49.

[2]. Quenelle, Debra C et al. Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice. Antimicrobial agents and chemotherapy vol. 51,2 (2007): 689-95.

[3]. Duraffour, Sophie et al. Tecovirimat, a p37 envelope protein inhibitor for the treatment of smallpox infection. IDrugs : the investigational drugs journal vol. 13,3 (2010): 181-91.

CoACoA of Tecovirimat
Smiles:C1[C@@H]2[C@H]1[C@@H]3C=C[C@H]2[C@@H]4[C@H]3C(=O)N(C4=O)NC(=O)C5=CC=C(C=C5)C(F)(F)F

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