TBQ3804

TQB3804 (EGFR-IN-7) ) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively. TQB3804 (EGFR-IN-7) shows anti-tumor activity.


Cat. No.: EX-A4322	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	550	In-stock
100mg	750	In-stock
250mg	1150	In-stock
500mg	1600	In-stock
1g	2600	In-stock
2g	4200	In-stock

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Synonyms	EGFR-IN-7
CAS No.	2267329-76-8
Purity	>98%
Formula	C32H41BrN9O2P
Mol Weight	694.605
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1] Xile Liu, et al. Abstract 1320: Preclinical evaluation of TQB3804, a potent EGFR C797S inhibitor. Cancer Res July 1 2019 (79) (13 Supplement) 1320; DOI: 10.1158/1538-7445.AM2019-1320 [2]. Ling WY, et, al. Prostaglandin E2 suppresses bacterial killing in alveolar macrophages by inhibiting NADPH oxidase. WO2019015655A1.
CoA	CoA of TBQ3804

Smiles:	CC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)C)OC)NC4=NC=C(C(=N4)NC5=C(C6=NC=CN=C6C=C5)P(=O)(C)C)Br


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