Chimmitecan

Chimmitecan is a potent topisomerase I inhibitor. Chimmitecan is also an active metabolite of simmitecan. Chimmitecan exhibits potent antitumor activities both in vitro and in vivo by inhibiting topoisomerase I.


Cat. No.: EX-A4320	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	350	In-stock
10mg	500	In-stock
25mg	800	In-stock
50mg	1100	In-stock
100mg	1500	In-stock
500mg	3000	In-stock

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CAS No.	185425-25-6
Purity	>98%
Formula	C23H20N2O5
Mol Weight	404.4153
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hu Z, Sun Y, Du F, Niu W, Xu F, Huang Y, Li C. Accurate determination of the anticancer prodrug simmitecan and its active metabolite chimmitecan in various plasma samples based on immediate deactivation of blood carboxylesterases. J Chromatogr A. 2011 Sep 23;1218(38):6646-53. doi: 10.1016/j.chroma.2011.07.042. Epub 2011 Jul 23. PubMed PMID: 21839460.
CoA	CoA of Chimmitecan

Smiles:	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CC=C)O)N=C4C3=C2)O


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