SX-682

SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity.


Cat. No.: EX-A4295	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	385	In-stock
250mg	650	In-stock
500mg	1050	In-stock
1g	1900	In-stock
2g	3500	In-stock
3g	4800	In-stock

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CAS No.	1648843-04-2
Purity	>98%
Formula	C19H14BF4N3O4S
Mol Weight	467.202
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sun L, et al. Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy. JCI Insight. 2019 Apr 4;4(7). [2]. Lu X, et al. Effective combinatorial immunotherapy for castration-resistant prostate cancer. Nature. 2017 Mar 30;543(7647):728-732.
CoA	CoA of SX-682

Smiles:	B(C1=C(C=C(C=C1)OC(F)(F)F)CSC2=NC=C(C=N2)C(=O)NC3=CC=C(C=C3)F)(O)O


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