| Synonyms | PF-06685360 |
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| CAS No. | 1527475-61-1 |
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| Purity | >98% |
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| Formula | C16H16N6O |
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| Mol Weight | 308.3378 |
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| Appearance | solid powder |
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| Solubility | Soluble in DMSO, not in water |
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| Shelf Life | >2 years if stored properly |
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| Storage | Powder -20℃ 3 years; In solvent -20℃ 1 month; |
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| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
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| Reference: | [1]. Marco A.S. Baptista, et al. LRRK2 Kinase Inhibitors of Different Structural Classes Induce Abnormal Accumulation of Lamellar Bodies in Type II Pneumocytes in Non-Human Primates but are Reversible and Without Pulmonary Functional Consequences.
[2]. Andersen MA, et al. Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation. Neurobiol Dis. 2018 Aug;116:13-27.
[3]. Andersen MA, et al. PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats. Toxicology. 2018 Feb 15;395:15-22. |
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| CoA | CoA of PFE-360 |
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Inhibitor Specialist 
