GPR81 agonist 1

GPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC50s of 58 nM and 50 nM for human and mouse GPR81, respectively. GPR81 agonist 1 inhibits lipolysis in differentiated 3T3-L1 adipocytes. GPR81 agonist 1 suppresses lipolysis in mice without cutaneous flushing. GPR81 agonist 1 displays remarkable selectivity for GPR81 over GPR109a


Cat. No.: EX-A4116	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	385	In-stock
25mg	665	In-stock
50mg	1050	In-stock
100mg	1550	In-stock
200mg	2450	In-stock
1g	3800	In-stock

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Synonyms	trans-4-methyl-n-[5-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-4-(2-thienyl)-1,3-thiazol-2-yl]cyclohexanecarboxamide
CAS No.	1620992-67-7
Purity	>98%
Formula	C22H30N4O2S2
Mol Weight	446.629
Appearance	solid powder
Solubility	Soluble in DMSO, not in water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sakurai T, et al. Identification of a novel GPR81-selective agonist that suppresses lipolysis in mice without cutaneous flushing. Eur J Pharmacol. 2014;727:1-7.
CoA	CoA of GPR81 agonist 1

Smiles:	O=C([C@H]1CC[C@H](C)CC1)NC2=NC(C3=CC=CS3)=C(CC(N4CCN(C)CC4)=O)S2


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