LC3-mHTT-IN-AN1

LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.


Cat. No.: EX-A4041	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	435	In-stock
250mg	785	In-stock
500mg	1150	In-stock
1g	1800	In-stock
2g	3000	In-stock
3g	3600	In-stock

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CAS No.	486443-73-6
Purity	>98%
Formula	C15H9Br2NO3
Mol Weight	411.045
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Nov;575(7781):203-209.
CoA	CoA of LC3-mHTT-IN-AN1

Smiles:	BrC1=CC=C(C/2=C1)NC(C2=C/C3=CC(Br)=C(C(O)=C3)O)=O


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