Product Information:
Cat. No.: EX-A4040 | Purity: >98% |
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Synonyms | APX-115 |
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CAS No. | 1270084-92-8 |
Purity | >98% |
Formula | C17H17N3O |
Mol Weight | 279.3364 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16;8(43):74217-74232.
[2]. Cha JJ, et al. APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury. Lab Invest. 2017 Apr;97(4):419-431. |
CoA | CoA of APX-115 free base |
Smiles: | OC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3 |
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