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Product Information:

APX-115 free base

APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor.

Cat. No.: EX-A4040    Purity: >98%
APX-115
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg500In-stock
100mg750In-stock
250mg1350In-stock


SynonymsAPX-115
CAS No.1270084-92-8
Purity>98%
FormulaC17H17N3O
Mol Weight279.3364
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16;8(43):74217-74232.

[2]. Cha JJ, et al. APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury. Lab Invest. 2017 Apr;97(4):419-431.
CoACoA of APX-115 free base
Smiles:OC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3

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