RBN-2397

RBN-2397 is a potent, selective and orally active NAD+ competitive inhibitor PARP7 with IC50 of <3 nM and Kd of <0.001 μM. RBN-2397 has the potential for the research of tumor treatment.


Cat. No.: EX-A4038	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	350	In-stock
250mg	600	In-stock
500mg	950	In-stock
1g	1650	In-stock
5g	4800	In-stock
10g	7680	In-stock

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CAS No.	2381037-82-5
Purity	>98%
Formula	C20H23F6N7O3
Mol Weight	523.4321
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Melissa Vasbinder, et al. RBN-2397: A First-in-Class PARP7 Inhibitor Targeting a Newly Discovered Cancer Vulnerability in Stress-Signaling Pathways. [2]. RBN-2397-Inhibiting PARP7, a Key monoPARP Cancer Dependency
CoA	CoA of RBN-2397

Smiles:	O=C1C(C(F)(F)F)=C(N[C@@H](C)COCCC(N2CCN(C3=NC=C(C(F)(F)F)C=N3)CC2)=O)C=NN1


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