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Product Information:

GRL0617

GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLpro)/deubiquitinase, with an IC50 of 0.6 μM, and with a Ki of 0.49 μM.

Cat. No.: EX-A4032    Purity: >98%
GRL0617
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg685In-stock
250mg985In-stock
500mg1385In-stock
1g1985In-stock
5g6950In-stock


CAS No.1093070-16-6
Purity>98%
FormulaC20H20N2O
Mol Weight304.3856
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ratia K, et al. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16119-24.

CoACoA of GRL0617
Smiles:O=C(N[C@@H](C1=C2C=CC=CC2=CC=C1)C)C3=CC(N)=CC=C3C

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