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Product Information:

JNK Inhibitor VIII

JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor (IC 50 values are 2, 4 and 52 nM for JNK1, JNK2 and JNK3 respectively).

Cat. No.: EX-A4018    Purity: >98%
JNK
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg700In-stock
250mg1000In-stock
500mg1450In-stock
1g2100In-stock
5g5950In-stock
10g9520inquire


SynonymsTCS JNK 6o
CAS No.894804-07-0
Purity>98%
FormulaC18H20N4O4
Mol Weight356.3758
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Szczepankiewicz BG1, Kosogof C, Nelson LT, Liu G, Liu B, Zhao H, Serby MD, Xin Z, Liu M, Gum RJ, Haasch DL, Wang S, Clampit JE, Johnson EF, Lubben TH, Stashko MA, Olejniczak ET, Sun C, Dorwin SA, Haskins K, Abad-Zapatero C, Fry EH, Hutchins CW, Sham HL, Rondinone CM, Trevillyan JM. Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. J Med Chem. 2006 Jun 15;49(12):3563-80.
CoACoA of JNK Inhibitor VIII
Smiles:N#CC1=C(N=C(NC(CC2=C(C=CC(OC)=C2)OC)=O)C=C1N)OCC

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