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Product Information:

GW6471

GW6471 is a potent PPARα antagonist.

Cat. No.: EX-A4011    Purity: >98%
GW6471
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg785In-stock
500mg1185In-stock
1g1885In-stock
5g5950In-stock
10g8825In-stock


SynonymsGW 6471
Synonyms 2436159-64-7
CAS No.880635-03-0
Purity>98%
FormulaC35H36F3N3O4
Mol Weight619.6732
Appearancesolid powder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Xu HE, et al. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. Nature. 2002 Feb 14;415(6873):813-7.

[2]. Abu Aboud O, et al. Inhibition of PPARα induces cell cycle arrest and apoptosis, and synergizes with glycolysisinhibition in kidney cancer cells. PLoS One. 2013 Aug 7;8(8):e71115.

[3]. Abu Aboud O, et al. PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth. Am J Physiol Cell Physiol. 2015 Jun 1;308(11):C890-8.

CoACoA of GW6471
Smiles:CCC(NC[C@@H](N/C(C)=C\C(C1=CC=C(C(F)(F)F)C=C1)=O)CC2=CC=C(OCCC3=C(C)OC(C4=CC=CC=C4)=N3)C=C2)=O

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