DPA-714

DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM). It is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. [18F]DPA-714 successfully assesses for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model.


Cat. No.: EX-A3761	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	1785	In-stock
200mg	2500	In-stock
500mg	get quote	In-stock
1g	get quote	Inquire

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CAS No.	958233-07-3
Purity	>98%
Formula	C22H27FN4O2
Mol Weight	398.4738
Appearance	solid powder
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. James, Michelle L et al. “DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization.” Journal of nuclear medicine : official publication, Society of Nuclear Medicine vol. 49,5 (2008): 814-22. [2]. Harhausen D, Sudmann V, Khojasteh U, Müller J, Zille M, Graham K, Thiele A, Dyrks T, Dirnagl U, Wunder A. Specific imaging of inflammation with the 18 kDa translocator protein ligand DPA-714 in animal models of epilepsy and stroke. PLoS One. 2013 Aug 2;8(8):e69529.
CoA	CoA of DPA-714

Smiles:	O=C(N(CC)CC)CC1=C2N=C(C)C=C(C)N2N=C1C3=CC=C(OCCF)C=C3


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