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Product Information:

NIK SMI1

NIK SMI1 is a highly potent and selective NF-κB-inducing kinase (NIK) inhibitor with Ki of 0.23 nM for NIK-catalyzed hydrolysis of ATP to ADP.

Cat. No.: EX-A3753    Purity: >98%
NIK
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg850In-stock
250mg1250In-stock
1g2650In-stock


CAS No.1660114-31-7
Purity>98%
FormulaC20H19N3O4
Mol Weight365.3826
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1] Blaquiere N, et al. Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase. J Med Chem. 2018 Aug 9;61(15):6801-6813.
CoACoA of NIK SMI1
Smiles:O=C(N)C1=NC(C2=CC=CC(C#C[C@]3(O)CCN(C)C3=O)=C2)=CC(OC)=C1

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