MT-802

MT-802 is a potent BTK degrader based on Cereblon ligand, with a DC50 of 1 nM. MT-802 has potential to treat C481S mutant chronic lymphocytic leukemia (CLL).


Cat. No.: EX-A3711	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	700	In-stock
50mg	900	In-stock
1g	get quote	In-stock
5g	get quote	In-stock
10g	get quote	Inquire

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CAS No.	2231744-29-7
Purity	>98%
Formula	C41H41N9O8
Mol Weight	787.8197
Appearance	white to off-white solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Buhimschi AD, et al. Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation. Biochemistry. 2018 Jul 3;57(26):3564-3575.
CoA	CoA of MT-802

Smiles:	O=C(NC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1)COCCOCCN4CCC(N5N=C(C6=CC=C(OC7=CC=CC=C7)C=C6)C8=C(N)N=CN=C85)CC4


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