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Product Information:

PF-06873600

PF-06873600 is an orally bioavailable, cyclin-dependent kinase (CDK) inhibitor, with potential antineoplastic activity.

Cat. No.: EX-A3695    Purity: >98%; ee>98%
PF-06873600
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg900In-stock
200mg1450In-stock
500mg2500In-stock
1g4200In-stock
5g15500In-stock
10g2450030 days


SynonymsPF3600
CAS No.2185857-97-8
Purity>98%; ee>98%
FormulaC20H27F2N5O4S
Mol Weight471.521
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Freeman-Cook, Kevin D et al. Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. Journal of medicinal chemistry vol. 64,13 (2021): 9056-9077.

[2]. Freeman-Cook, Kevin et al. Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor. Cancer cell vol. 39,10 (2021): 1404-1421.e11.

CoACoA of PF-06873600
Smiles:O=S(N1CCC(NC2=NC3=C(C=C(C(F)F)C(N3[C@@H]4CCC[C@]4(O)C)=O)C=N2)CC1)(C)=O

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