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Product Information:

NVS-PAK1-1

NVS-PAK1-1 is a potent and selective allosteric PAK1 inhibitor with an IC50 of 5 nM.

Cat. No.: EX-A3547    Purity: >98%
NVS-PAK1-1
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg485In-stock
250mg900In-stock
500mg1380In-stock
1g1980In-stock
5g6500In-stock


CAS No.1783816-74-9
Purity>98%
FormulaC23H25ClF3N5O
Mol Weight479.926
Appearancesolid powder
SolubilitySoluble in DMSO, >100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Karpov AS, et al. Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. ACS Med Chem Lett. 2015 May 22;6(7):776-81.

CoACoA of NVS-PAK1-1
Smiles:FC1=CC2=C(C=C1)N(CC(F)F)C3=C(C=C(Cl)C=C3)C(N[C@H]4CCN(C(NC(C)C)=O)C4)=N2

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