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Product Information:

DMX-5084

DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor with IC50 of 3 nM for human MAP4K4.

Cat. No.: EX-A3537    Purity: >99.5%
DMX-5084
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg685In-stock
200mg985In-stock
500mg1385In-stock
1g1985In-stock
5g5250In-stock
10g7875In-stock


CAS No.2306178-56-1
Purity>99.5%
FormulaC21H19N3O3
Mol Weight361.3939
Appearancewhite solid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Fiedler LR, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush PA, Bellahcene M, Noseda M, Faust D, Jarvis A, Newton G, Paiva MA, Harada M, Stuckey DJ, Song W, Habib J, Narasimhan P, Aqil R, Sanmugalingam D, Yan R, Pavanello L, Sano M, Wang SC, Sampson RD, Kanayaganam S, Taffet GE, Michael LH, Entman ML, Tan TH, Harding SE, Low CMR, Tralau-Stewart C, Perrior T, Schneider MD. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo. Cell Stem Cell. 2019 Apr 4;24(4):579-591.e12. doi: 10.1016/j.stem.2019.01.013. Epub 2019 Mar 7. Erratum in: Cell Stem Cell. 2020 Mar 5;26(3):458. PMID: 30853557; PMCID: PMC6458995.
Data SheetData sheet of DMX-5084
CoACoA of DMX-5084
Smiles:O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4

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