AZ32

AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.


Cat. No.: EX-A1895	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
500mg	765	In-stock
1g	1100	In-stock

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CAS No.	2288709-96-4
Purity	>98%
Formula	C20H16N4O
Mol Weight	328.3672
Appearance	Solid powder
Solubility	DMSO > 150 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Karlin J, et al. Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice. Mol Cancer Ther. 2018 Aug;17(8):1637-1647.
CoA	CoA of AZ32

Smiles:	CNC(=O)C1=CC=C(C=C1)C1=CN=C2C=NC(=CN12)C1=CC=CC=C1


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