LMP400

Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.


Cat. No.: EX-A3020	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	550	In-stock
100mg	800	In-stock
200mg	1200	In-stock
500mg	1800	In-stock
1g	2800	In-stock
5g	Get quote	In-stock

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Synonyms	Indotecan
Synonyms 2	NSC-724998
CAS No.	915303-09-2
Purity	>98%
Formula	C26H26N2O7
Mol Weight	478.4938
Appearance	Solid powder
Solubility	DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Balaña-Fouce R, et, al. Indotecan (LMP400) and AM13-55: two novel indenoisoquinolines show potential for treating visceral leishmaniasis. Antimicrob Agents Chemother. 2012 Oct;56(10):5264-70. [2]. Seol Y, et, al. Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors. Mol Cancer Ther. 2015 Nov;14(11):2552-9.
CoA	CoA of LMP400

Smiles:	COC1=C(OC)C=C2C(=O)N(CCCN3CCOCC3)C3=C(C(=O)C4=C3C=C3OCOC3=C4)C2=C1


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