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Product Information:

Belumosudil

Belumosudil (KD025) is a selective inhibitor of ROCK2 with IC50s of 105 nM and 24 µM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties.

Cat. No.: EX-A2314    Purity: >98%
Belumosudil
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg395In-stock
250mg495In-stock
500mg695In-stock
1g965In-stock
5g1850In-stock
10g2850In-stock


SynonymsKD-025
Synonyms 2SLx-2119
CAS No.911417-87-3
Purity>98%
FormulaC26H24N6O2
Mol Weight452.5078
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Boerma, M., et al. Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase. Blood Coagul Fibrinolysis. 2008 Oct;19(7):709-18.

[2]. Lee, J.H., et al. Selective ROCK2 Inhibition In Focal Cerebral Ischemia. Ann Clin Transl Neurol. 2014 Jan 1;1(1):2-14.
CoACoA of Belumosudil
Smiles:CC(C)NC(=O)COC1=CC=CC(=C1)C1=NC(NC2=CC3=C(NN=C3)C=C2)=C2C=CC=CC2=N1

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