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Product Information:

Pemafibrate

Pemafibrate is a highly specific PPARα agonist (EC50: 1 nM).

Cat. No.: EX-A1919    Purity: >98%
Pemafibrate
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg485In-stock
50mg800In-stock
100mg1200In-stock
250mg1850In-stock
500mg2650In-stock
1g3850In-stock


CAS No.848259-27-8
Purity>98%
FormulaC28H30N2O6
Mol Weight490.5476
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yamazaki, Yukiyoshi et al. “Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists.” Bioorganic & medicinal chemistry letters vol. 17,16 (2007): 4689-93.

[2]. Honda, Yasushi et al. “Pemafibrate, a novel selective peroxisome proliferator-activated receptor alpha modulator, improves the pathogenesis in a rodent model of nonalcoholic steatohepatitis.” Scientific reports vol. 7 42477. 14 Feb. 2017

[3]. Sairyo, Masami et al. “A Novel Selective PPARα Modulator (SPPARMα), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice.” Journal of atherosclerosis and thrombosis vol. 25,2 (2018): 142-152.

CoACoA of Pemafibrate
Smiles:CC[C@@H](OC1=CC=CC(CN(CCCOC2=CC=C(OC)C=C2)C2=NC3=CC=CC=C3O2)=C1)C(O)=O

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